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(D81.3) Adenosine deaminase [ada] deficiency
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37 763 in individuals diagnosis adenosine deaminase [ada] deficiency confirmed
2 729 deaths with diagnosis adenosine deaminase [ada] deficiency
7% mortality rate associated with the disease adenosine deaminase [ada] deficiency
Diagnosis adenosine deaminase [ada] deficiency is diagnosed Men are 25.48% more likely than Women
23 693
Men receive the diagnosis adenosine deaminase [ada] deficiency
926 (3.9 %)Died from this diagnosis.
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14 070
Women receive the diagnosis adenosine deaminase [ada] deficiency
1 803 (12.8 %)Died from this diagnosis.
Risk Group for the Disease adenosine deaminase [ada] deficiency - Men aged 20-24 and Women aged 0-5
In Men diagnosis is most often set at age 0-14, 20-89
Less common in men the disease occurs at Age 15-19, 90-95+Less common in women the disease occurs at Age 55-59, 90-95+
In Women diagnosis is most often set at age 0-54, 60-89
Disease Features adenosine deaminase [ada] deficiency
Absence or low individual and public risk
Adenosine deaminase [ada] deficiency - what does this mean
Adenosine deaminase (ada) deficiency is a rare genetic disorder caused by a mutation in the ada gene, which results in the inability of the body to produce the enzyme adenosine deaminase. this enzyme is necessary for the proper functioning of the immune system, as it helps to break down certain molecules that are essential for the development and maintenance of the immune system. without ada, the immune system cannot function properly, leading to a wide range of serious and even life-threatening symptoms.
What happens during the disease - adenosine deaminase [ada] deficiency
Adenosine deaminase (ada) deficiency is an inherited disorder caused by a genetic mutation in the ada gene, which produces the enzyme adenosine deaminase. this enzyme is responsible for breaking down the purine nucleotide adenosine, which is essential for the production of dna and rna. without ada, adenosine accumulates in the body and interferes with the production of dna and rna, leading to the development of a wide range of symptoms, including immune system dysfunction, neurological problems, and bone marrow failure.
Clinical Pattern
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How does a doctor diagnose
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Treatment and Medical Assistance
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19 Days of Hospitalization Required
48 Hours Required for Outpatient Treatment
Adenosine deaminase [ada] deficiency - Prevention
Ada deficiency can be prevented by genetic counseling and prenatal testing. counseling should be offered to families with a history of the disorder and prenatal testing should be done to detect the presence of the gene mutation. additionally, newborn screening should be done to identify affected individuals and to provide early diagnosis and treatment.